Review evidence, classify variants, and generate structured reports in one environment.
Complete answers. For every patient. Every time.
Spend less time on routine, and more time on the work only you can do. Vgen23 frees you from tools management so you can provide answers for every patient, knowing that everything is fully secure with international standards.
Generating data is no longer the hardest part. Interpretation, review, and reporting still happen across fragmented tools, manual checks, and report templates that slow your team down.
ClinVar, gnomAD, OMIM, PubMed, IGV, spreadsheets, internal notes. Critical evidence is spread across tools that were never built to work together.
Automated scoring helps, but someone still has to verify criteria, inspect the evidence, and make sure every call is traceable.
Variants of uncertain significance accumulate quickly, but most workflows do not give teams a structured way to review, revisit, and respond over time.
Patient details, evidence references, OMIM links, and report formatting are often stitched together manually when they should already be part of the workflow.
Vgen23 brings your entire interpretation workflow into a single workspace. Stop switching tabs.
Start reviewing variants.
Each variant annotated against 100+ databases - ClinVar, gnomAD, OMIM, PubMed, Indian Genome AF, and more. Population frequency, functional predictions, conservation scores - all traceable to source.
Apply ACMG/AMP criteria with a visible evidence trail. Review triggered criteria, inspect supporting evidence, and keep every change audit-logged.
A network visualization of relationships across your case. Spot convergent evidence. Identify shared phenotypes across candidate genes. Prioritize visually instead of scanning rows.
Type clinical text as it appears in a referral note. The platform maps it to standardized HPO terms - in English, Hindi, Tamil, or other native scripts. No manual HPO lookup.
Integrated IGV browser for every variant. Confirm read alignment and sequencing quality without leaving the analysis.
Select variants, add to report, download as PDF. Case information, evidence references, and OMIM IDs populate automatically. Your template. Your branding. Consistent every time.
Phenotype-to-genotype and genotype-to-phenotype review in one workflow.
Family-based review with de novo and segregation support.
Structured interpretation for disease-specific panels.
Interpretation support for somatic workflows with tumor-focused reporting.
Global reference databases still underrepresent South Asian populations. Vgen23 integrates Indian Genome allele frequency data alongside widely used global databases so interpretation decisions reflect the population your lab actually serves.
Performance claims are specific, reviewable, and tied to real evaluation cohorts.
100-patient cohort. 130 evaluated sites. 99.1% sensitivity. 100% specificity. Vgen23 detected 112 of 113 true positive variants with no false positives.
96 lung cancer patients. 119,022 somatic variants evaluated. 99.6% sensitivity.
39 individuals with affected and unaffected controls. 93.1% sensitivity. 100% specificity. Affected variants ranked in the top 1 to 5.
Most detected variants ranked in the top 1 to 20, with 63% in the top 1 to 5.
Vgen23 runs with documented security controls, auditability, and a full trust package available through our Trust Center.
Create an account, upload a VCF, and evaluate Vgen23 on your own cases.
No sales call required.
WES from 2,500 credits | 3,000 free credits to start
See Full Pricing →Vgen23 is built by the internationally recognized team at Vgenomics, a biotech company built by scientists from India and the US, accelerating discoveries for genetic diseases.
Learn more about the company behind Vgen23
About VgenomicsVgen23 Blog
Authors: Kartik Pal, Dr. Varun Venkat, Dr. Rahila Sardar · Published: 2026 · Reading time: ~12 min Abstract Phenotype-driven variant prioritization is a cornerstone of clinical gen...
Author: Rahila Sardar, PhD — Co-Founder and CEO · Published: April 2026 · Reading time: ~14 min Abstract The cost of whole-genome sequencing reagents has fallen below $300 per geno...
Upload your own case to see how Vgen23 ranks and structures the review,
and evaluate it on your current workflow.
Free Trial. All Premium Features. 3,000 credits.
2 minutes to create an account. Instant access.
